Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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6,751 – 6,765 of 178,220 results

6,751

eMolecules 712-30-1 | 6-Formylpterin | Medchem Express (US) | MFCD00038691 | 191.150 | C7H5N5O2 | 98.000 | Nc1nc2ncc(C=O)nc2c(=O)[nH]1 | 10mg | 857185363

6-Formylpterin | Medchem Express (US) | 712-30-1 | MFCD00038691 | 191.150 | C7H5N5O2 | 98.000 | Nc1nc2ncc(C=O)nc2c(=O)[nH]1 | 10mg | 857185363

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6,752

eMolecules 808118-40-3 | Roxadustat | Target Molecule | MFCD20040519 | 352.346 | C19H16N2O5 | 0.000 | Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12 | 50mg | 335411898

Roxadustat | Target Molecule | 808118-40-3 | MFCD20040519 | 352.346 | C19H16N2O5 | 0.000 | Cc1nc(C(=O)NCC(O)=O)c(O)c2ccc(Oc3ccccc3)cc12 | 50mg | 335411898

Pricing & Availability

6,753

eMolecules 920868-45-7 | MASM7 | Ambeed453.580 | C22H23N5O2S2 | 99.000 | CC(Sc1nnc(C2CC2)n1-c1ccccc1)C(=O)Nc1sc2CCCc2c1C(N)=O | 25mg | 854182311

MASM7 | Ambeed | 920868-45-7453.580 | C22H23N5O2S2 | 99.000 | CC(Sc1nnc(C2CC2)n1-c1ccccc1)C(=O)Nc1sc2CCCc2c1C(N)=O | 25mg | 854182311

Pricing & Availability

6,754

eMolecules 2049980-18-7 | Azelaprag | Medchem Express523.610 | C25H29N7O4S | 98.000 | COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)nnc1-c1cncc(C)c1 | 5mg | 801132161

Azelaprag | Medchem Express | 2049980-18-7523.610 | C25H29N7O4S | 98.000 | COc1cccc(OC)c1-n1c(NS(=O)(=O)[C@@H](C)[C@H](C)c2ncc(C)cn2)nnc1-c1cncc(C)c1 | 5mg | 801132161

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6,755

Apexbio Technology LLC SC 560 188817-13-2 10mg

SC 560 (CAS 188817-13-2) is a selective inhibitor of cyclooxygenase-1 (COX-1) exhibiting an IC50 of 0 009 M for COX-1 and 6 3 M for COX-2 By preferentially blocking COX-1 activity SC 560 impedes the conversion of arachidonic acid to prostaglandins such as thromboxane and PGE2 In vitro studies demonstrate that SC 560 suppresses COX-1-derived prostaglandin generation in a concentration-dependent manner inhibits cellular proliferation and induces apoptosis In vivo administration results in complete inhibition of COX-1-mediated thromboxane B2 and PGE2 production and attenuation of tumor growth in ovarian epithelial cancer models SC 560 serves as a valuable tool for investigating COX-1 s roles in inflammation pain and tumorigenesis

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6,756

Medchemexpress LLC 4-quinolinecarboxamide, 2-(4-ethoxyphenyl)-n-[3-(2-methyl-1-piperidinyl)propyl]- | 689270-18-6 | 99.9% | 431.57 g/mol | C27H33N3O2 | 10 MG

IRF5-IN-1 is a small-molecule research compound that blocks IRF5 activation and downstream TLR7/8 signaling, producing anti-inflammatory effects observed in in vitro studies. Supplied as an off-white to light yellow solid, it is intended for biochemical and cell-based assays after dissolution in appropriate solvents (DMSO recommended). Follow recommended storage and handling conditions for experimental reproducibility.

Selective inhibition of IRF5-mediated signaling in cellular assays.
High purity (~99.9%) suitable for research applications.
Soluble in DMSO at 50 mg/mL with ultrasonic warming to 80°C.
Supplied as a 10 mg powder for small-scale experiments.
Stable when stored as powder at -20°C, with defined in-solution stability.
Useful tool for studying TLR7/8-IRF5 inflammatory pathways.

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6,757

Medchemexpress LLC Somatostatin-28 (sheep, human rat mouse) | 73032-94-7 | 99.7% | 3148.56 | 10 MG

Somatostatin-28 is a biologically active polypeptide, synthesized in the proximal intestinal epithelial cells. It suppresses glucose-stimulated insulin secretion without affecting circulating basal insulin concentration, and targets somatostatin receptor subtype 5 (SSTR5) to regulate GLP-1 secretion.

Biologically active polypeptide
Synthesized in proximal intestinal epithelial cells
Suppresses glucose-stimulated insulin secretion
Does not affect circulating basal insulin concentration
Targets somatostatin receptor subtype 5 (SSTR5)
Regulates GLP-1 secretion

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6,758

Medchemexpress LLC (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide | 173529-46-9 | 99.9% | 10 MG

HMN-214 is an orally bioavailable prodrug of HMN-176 that inhibits polo-like kinase 1 (PLK1) and demonstrates antitumor activity. Supplied as a solid research compound with high purity, defined storage conditions, and recommended solvent for handling.

Orally bioavailable prodrug with PLK1 inhibitory activity.
High purity available (99.9%).
Molecular weight 424.47 and formula C22H20N2O5S.
Soluble in DMSO (~8.33 mg/mL); ultrasonic assistance recommended.
Store powder at -20°C for long-term stability.

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6,759

Apexbio Technology LLC GSK2126458(Synonyms: Omipalisib, GSK-2126458, GSK 2126458, Omipalisib (GSK2126458)), 10mg, CAS: 1086062-66-9.

GSK2126458 (CAS 1086062-66-9) is a small molecule inhibitor targeting PI3K and mTOR pivotal regulators in cell growth proliferation and tumor progression GSK2126458 demonstrates potent inhibitory activity against PI3K (Ki 19 pM) In colon cancer cells combined use with DDR1-IN-1 enhances its antiproliferative effects Additionally the compound induces G1 phase arrest in BT474 breast cancer cells and sensitizes nasopharyngeal carcinoma (NPC) cell lines to radiation therapy In vivo studies show that combining GSK2126458 with radiation or with MEK and BRAF inhibitors suppresses tumor growth GSK2126458 also influences cellular autophagy pathways highlighting its utility in oncology-focused biomedical research

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6,760

Medchemexpress LLC 1-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole | 2411969-39-4 | 99.3% | 282.05 | C9H4Cl2F3N3 | 10 MG

ARUK3001185 is a potent, selective Notum inhibitor developed for research into Wnt signaling and related biological pathways. It is orally active and brain-penetrant, with an IC50 of 6.7 nM, and has demonstrated in vivo exposure in plasma and brain after oral dosing. The compound is supplied as a high-purity solid suitable for biochemical assays and in vivo studies.

Potent, selective inhibitor of Notum (IC50 = 6.7 nM).
Orally active and brain-penetrant.
Restores Wnt signaling in vitro.
Demonstrated plasma and brain exposure in mouse studies after oral dosing.
High purity suitable for research use (≈99.3%).
Available in multiple solid quantities for dosing and screening.

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6,761

Frontier Specialty Chemicals 5G 4-BROMOPYRIDINE-2-CARBOXYLI

4-Bromopyridine-2-carboxylic acid; CAS No: 30766-03-1

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6,762

Medchemexpress LLC PKM2 MOUSE BACULOV 5UG

5000195880 PKM2 MOUSE BACULOV 5UG

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6,763

Medchemexpress LLC (S)-2-(1,4-dibenzylpiperazin-2-yl)acetonitrile | 2225787-92-6 | 99.9% | 305.43 | C20H23N3 | 100 MG

(S)-2-(1,4-dibenzylpiperazin-2-yl)acetonitrile is a chiral drug intermediate used in the synthesis of active pharmaceutical compounds and for laboratory research applications.

High purity (99.9% by LCMS).
Molecular formula C20H23N3, molecular weight 305.43.
Identified uses: laboratory chemicals and manufacture of substances.
Appearance oil; reported boiling point ≈462.6 ± 30.0 °C (760 mmHg).
Recommended storage: pure form -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).

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6,764

Medchemexpress LLC STREPTOKINASE G STR 5UG

5000195804 STREPTOKINASE G STR 5UG

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6,765

Medchemexpress LLC 1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-(piperazinyl)urea | 1173204-81-3 | MFCD18251484 | 99.2% | 570.65 | C29H34N10O3 | 50 MG

A selective, reversible, ATP-competitive small-molecule inhibitor of class I PI3K isoforms and mTOR, exhibiting low-nanomolar potency against PI3Kα (including H1047R and E545K mutants), PI3Kβ, PI3Kγ, PI3Kδ, and mTOR. Intended for research use in biochemical and cellular studies of PI3K/mTOR signaling.

Low-nanomolar potency (PI3Kα 2 nM; PI3Kβ 7 nM; PI3Kγ 16 nM; PI3Kδ 14 nM; mTOR 3 nM).
Active against clinically relevant PI3Kα mutants (H1047R, E545K).
Reversible, ATP-competitive mechanism suitable for kinase assays.
High purity (99.17%) for reliable experimental results.
Characterized molecular formula C29H34N10O3 and molecular weight 570.65.
Suitable for biochemical, cellular, and target-validation studies.

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Pyridines and derivatives

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Apexbio Technology LLC SC 560 188817-13-2 10mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 4-quinolinecarboxamide, 2-(4-ethoxyphenyl)-n-[3-(2-methyl-1-piperidinyl)propyl]- | 689270-18-6 | 99.9% | 431.57 g/mol | C27H33N3O2 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Somatostatin-28 (sheep, human rat mouse) | 73032-94-7 | 99.7% | 3148.56 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (E)-4-(2-(N-((4-methoxyphenyl)sulfonyl)acetamido)styryl)pyridine 1-oxide | 173529-46-9 | 99.9% | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC GSK2126458(Synonyms: Omipalisib, GSK-2126458, GSK 2126458, Omipalisib (GSK2126458)), 10mg, CAS: 1086062-66-9. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-[2,4-dichloro-3-(trifluoromethyl)phenyl]-1H-1,2,3-triazole | 2411969-39-4 | 99.3% | 282.05 | C9H4Cl2F3N3 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PKM2 MOUSE BACULOV 5UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-2-(1,4-dibenzylpiperazin-2-yl)acetonitrile | 2225787-92-6 | 99.9% | 305.43 | C20H23N3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC STREPTOKINASE G STR 5UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-[4-(3-ethyl-7-morpholin-4-yltriazolo[4,5-d]pyrimidin-5-yl)phenyl]-3-(piperazinyl)urea | 1173204-81-3 | MFCD18251484 | 99.2% | 570.65 | C29H34N10O3 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More